Oocyte euploidy, pronuclear zygote morphology and embryo chromosomal complement
نویسندگان
چکیده
منابع مشابه
Influence of patient age on the association between euploidy and day-3 embryo morphology.
A retrospective cohort study conducted in 138 patients undergoing their first preimplantation genetic screening (PGS) cycle between January 1, 2006, and December 31, 2007, demonstrated that embryos with good day-3 morphology were more likely to be euploid for X/Y, 8, 15, and 18 than those with poor morphology. The strength of association between euploidy and day-3 morphology was not influenced ...
متن کاملAnalysis of pronuclear zygote configurations in 459 clinical pregnancies obtained with assisted reproductive technique procedures
BACKGROUND Embryos selection is crucial to maintain high performance in terms of pregnancy rate, reducing the risk of multiple pregnancy during IVF. Pronuclear and nucleolar characteristics have been proposed as an indicator of embryo development and chromosomal complement in humans, providing information about embryo viability. METHODS To correlate the zygote-score with the maternal age and ...
متن کاملPronuclear morphology evaluation in in vitro fertilization (IVF) / intracytoplasmic sperm injection (ICSI) cycles: a retrospective clinical review
UNLABELLED BACKGROUND The assessment of the embryo quality is crucial to maintain an high pregnancy rate and to reduce the risk of multiple pregnancy. The evaluation of the pronuclear and nucleolar characteristics of human zygote have been proposed as an indicator of embryo development and chromosomal complement. The aim of the current study was to assess the role of pronuclear morphology ev...
متن کاملThe successful use of pronuclear embryo transfers the day following oocyte retrieval.
A retrospective analysis of results from 114 initiated in-vitro fertilization cycles utilizing pronuclear embryo transfer is presented. Patients were unselected for age or infertility criteria, constituted a continuous series and were grouped according to response to stimulation (Group 1, ideal; Group 2, suboptimal) or ovarian reserve (Group 3, poor). At 16-18 h post-insemination, embryos were ...
متن کاملThe effect of pronuclear morphology on early development and chromosomal abnormalities in cleavage-stage embryos.
BACKGROUND Pronuclear (PN) zygote morphology has been proposed as a useful tool for selecting the best embryos for transfer. METHODS PN morphology was recorded in 888 zygotes and classified according to similar/different PN size [groups A (n = 816) and B (n = 72)] and to the number, distribution and synchrony of nucleolar precursor bodies (NPB): subgroup I, pronuclei with 3-4 polarized NPB; s...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2006
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/del334